CDC Travel Site
First off, you'll want to be up-to-date on routine vaccines, which I am. Secondly, the vaccines recommended for the majority of travelers are:
- Hepatitis A
- Typhoid
On the off chance that you might need a medical procedure in Guatemala, you may want to consider HepB as well. I already had them as a routine vaccinations, so I don't need those. Water purification tablets are also advisable. Depending on the area you'll be visiting, malaria drugs may be helpful as well. There is only one day of my trip that I will be in a risky area, so I am still debating whether it's worth it. I may just take extreme mosquito precautions in regards to clothing, sprays, etc. on that one day.
There are diseases in Guatemala spread by mosquitoes with no vaccines, so be sure to take extra precautions in regards to clothing and mosquito repellants even if you aren't in a malarial area! Also note: If you donate blood, travel to malarial areas restricts you from donating for a year.
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